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A notable study, the BRAVES trial, demonstrated histological improvement in MASH without worsening of fibrosis in 55 % of patients undergoing Roux-en-Y gastric bypass or sleeve gastrectomy after one year, compared to only 15 % in patients who undertook lifestyle modification alone [202]

Biotechnol Bioeng 2021;118:1393404

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Ghusn W, De la Rosa A, Sacoto D, Cifuentes L, Campos A, Feris F, Hurtado MD, Acosta A

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