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These differences may be related to the expression level of GLP-1R on the surface of different tumor cells (75, 98) and may be related to the differences in the results caused by the differences in the cell lines studied, the differences in the study population, and other factors

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The study period on medication or placebo following the lifestyle intervention is 72 weeks (84)

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Diuretic Action of Sodium-Glucose Cotransporter 2 Inhibitors and Its Importance in the Management of Heart Failure

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The half-life of approximately six days means doubling produces plasma levels significantly higher than intended, increasing side effect risk without proportional benefit

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The most important effect of GLP-1 is to increase insulin secretion after a meal, and this effect is dependent on glucose concentration, so despite promoting insulin secretion, the occurrence of hypoglycemia is rare [25]

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