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Several GLP-1 medications are FDA-approved for either Type 2 diabetes or chronic weight management when certain conditions are met

However, thousands of people were prescribed the drug before these warning label updates

Most are taken once a week

Its a powerful concept, but it comes with a shadow of dread

In the LEADER study with liraglutide, in the evaluation of cardiovascular events [n = 9340 patients, 50 years with established cardiovascular disease (coronary event, cerebrovascular event, or peripheral vascular disease), stage 3 chronic kidney disease, or chronic heart failure according to New York Heart Association class II or III or 60 years with at least one cardiovascular risk factor (CVRF)], liraglutide demonstrated a significant reduction in MACE by 13% at the expense of a reduction in cardiovascular mortality