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In addition to the reduction in body weight, improvement in liver injury rates and resolution of steatohepatitis in 39% of cases, treatment with liraglutide was associated with lower progression of liver fibrosis compared to placebo

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The necessity for apical glucose transport is demonstrated in Sglt1 / mice, where glucose-stimulated GIP secretion is eliminated and levels rise only to the same extent as observed in the saline control (Gorboulev et al., 2012)

Participants in major trials lost anywhere from 15% to over 20% of their body weight, results that had previously only been associated with bariatric surgery