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Description
Among the numerous major discoveries made in this regard was the finding that the hyperglycemic effect of glucagon resides in its ability to act in the liver to stimulate glycogenolysis and gluconeogenesis [[6], [7], [8], [9], [10], [11], [12]] despite its seemingly paradoxical ability to stimulate insulin secretion in humans reported by Ellis Samols in 1965 [13]
10.1016/j.arth.2023.12.023 [DOI] [PubMed] [Google Scholar] 61.Hulst AH, Plummer MP, Hollmann MW, DeVries JH, Preckel B, Deane AM et al (2018) Systematic review of incretin therapy during peri-operative and intensive care
This study does not require ethical review or approval but must comply with relevant laws and regulations
The presence of unwanted adverse effects It has been suggested that switching from one GLP1RA to another may result in resolution of GI adverse effects
Shah Drafting of the manuscript: Zahra Nazir, Ushna Gul, Muddasir Mohammed Fariduddin, Mohamed Alansaari, Ashraf Ullah, Esal Marroqun Len, Daanyal N
