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This is one of the reasons it is different from GLP-1-only treatments
Brain-derived neurotrophic factor (BDNF) is important for neurogenesis, and various depressive symptoms arise from decreased BDNF levels (Sahay and Hen, 2007)
However, due to the lack of research data at present, and because the mechanism underlying the action of DPP-4iDPP-4i upon BP is complex, further studies are now needed to identify the precise mechanism involved
March 2021
