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Factors that Reduce Ghrelin Likewise, some factors have been associated with decreased ghrelin production or release in humans

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Dosing & infusion rate Start short-acting IV insulin at a fixed weight-based dosing of 0.1 U/kg/hr (up to a maximum of 15 units/h in morbid obesity) *

At least two documented outpatient RLS diagnoses were required for inclusion

Body Mass Index (BMI): You have a documented body mass index (BMI) of 30 kg/m2 or higher, or your initial BMI is 27 kg/m2 or higher with at least one weight-related comorbid condition, such as a documented medical history of high blood pressure, high cholesterol, type 2 diabetes mellitus, or obstructive sleep apnea