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A meta-analysis of GLP-1RA CVOT showed that treatment with GLP-1RA reduced the risk of developing a composite kidney outcome including new-onset MA by 21% compared to placebo (HR 0.79, 95% CI 0.73-0.87), with only ELIXA and EXSCEL not achieving significant benefit [11]
Both Kaufman and Ruhoy believe the key may lie in the drugs ability to attach to and stabilize mast cells
In Phase 2 trials, treatment with survodutide led to greater reductions in both HbA1c levels and body weight compared to placebo after 16 weeks
Her goal is to empower patients through knowledge, safety, and personalized care.
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