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GLP-1 receptor agonists were developed primarily to treat type 2 diabetes and were later approved for chronic weight management

Across the RCTs, CoQ10 dropped: Systolic BP by 16.6 mm Hg Diastolic BP by 8.2 mm Hg (both with no change in the placebo group) In the crossover study, CoQ10 dropped: Systolic BP by 11 mm Hg Diastolic BP by 8 mm Hg Even in open-label studies (less controlled), CoQ10 dropped: Systolic BP by 13.5 mm Hg Diastolic BP by 10.3 mm Hg These numbers are on par with most commonly prescribed antihypertensive (blood pressure) drugs

One major study called the FLOW trial found that GLP-1 medications reduced kidney problems by 24 percent in people with diabetes

Instead, distribute your water intake throughout the entire day

But there are also some lesser-known side effects catching patients off guard