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Smaller pharmacies were required to stop making semaglutide by April 22, while larger operations had a deadline of May 22

After the meal event, satiety gradually drops over time and hunger returns, starting a new cycle [32]

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The difference was about 3 to 4 additional cases per 10,000 patients over 18 months , with the apparent excess risk more concentrated in older adults, men, and people with more advanced diabetes or existing eye or cardiovascular conditions