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72,73 The increase in intracellular cAMP after GLP-1R activation then activates a guanine nucleotide exchange factor called Epac (Exchange Protein directly Activated by cAMP), which induces PI3K activation followed by Akt phosphorylation

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Ozempic is approved to lower blood sugar in adults with type 2 diabetes and to reduce the risk of heart attack or stroke in patients with diabetes and heart disease

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Even with initial adoption focused on higher-income segments, the potential market could reach over 5,000 crore, driven by Indias large and increasingly overweight population