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The LES acts as a valve, opening to allow food into the stomach and closing to prevent stomach contents from flowing back up

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This happens because semaglutide slows down how fast food moves through the stomach

Code availability Code for preprocessing SomaScan proteomics data, performing statistical analyses and generating figures is available via Zenodo at (ref

[DOI] [PubMed] [Google Scholar] 525.Anderson CS, Heeley E, Huang Y, et al Rapid blood-pressure lowering in patients with acute intracerebral haemorrhage