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Among people who are considering a joint replacement, semaglutide or tirzepatide could help them attain a safer weight prior to surgery, or even relieve pain enough to delay surgery for a few years or negate the need for it all together

The important takeaway here is that these drugs help manage the metabolic conditions that contribute to weight gain, but do not permanently cure them

"FDA Approves New Medication for Chronic Weight Management." FDA.gov CVS Caremark

Thus, studies have shown that at high doses administered over a prolonged period, the increase in Bifidobacteria is associated with improvements in these values, especially body weight and BMI [17,24]

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