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The pathophysiology of BPPV involves dislodgement of otoconia from the utricle, a process in which glycemic status may play a contributory role 17

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The SURPASS clinical trial program, which evaluated tirzepatide for type 2 diabetes over periods extending to 52 weeks and beyond, demonstrated sustained glycemic improvements without evidence of significant tachyphylaxis (rapid tolerance development) for the primary glucose-lowering effects