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Notably, the majority of mechanistic data supporting this concentration-dependent model derives from preclinical studies using mouse pancreatic -cells and clonal cell lines, with limited validation in human islet studies, necessitating further clinical investigation to confirm these concentration thresholds in human diabetes treatment [23,24,25,26]

95% confidence interval (CI), 1.231.52)

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The NY Times article optimistically stated: Relief should be coming soon, health economists predict, with companies rushing to develop their own drugs