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In patients in whom the above-mentioned interventions are insufficient to control the manifestations of HF, additional mechanical circulatory support and/or cardiac transplantation may be indicated

MLM received lecture or consultancy fees from Amarin, AstraZeneca, Lilly, Merck, Sharp & Dohme, Mylan, Novartis and Novo Nordisk

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The doctors diagnosed him with ileus (a type of bowel obstruction) and gastroparesis

For the GLP-1R V229A, however, we observed a higher proportion of receptors pre-existing as higher order oligomers under vehicle conditions, with no further increases after exendin-4 stimulation, indicating that the mutant receptor has a higher clustering propensity in the inactive state