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These medications mimic a hormone called GLP-1 that naturally occurs in the body and helps regulate blood sugar levels and appetite

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If you have Type 2 diabetes, you may already have coverage

Importantly, a meta-analysis of 14 clinical trials evaluating gastrointestinal adverse effects of GLP-1RAs found that long-acting agents had lower rates of nausea and vomiting than short-acting formulations

Why this matters for choice: The additional GIP mechanism is why some patients who do not respond adequately to Wegovy may respond better to Mounjaro a different enough mechanism that partial responders to one may be full responders to the other