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However, the underlying mechanism has not been fully elucidated

( Epub 2011 Feb 18
In lupus, obesity has been linked to more frequent flares and greater organ involvement

The definitive impact of tirzepatide on cardiovascular disease will be addressed in the ongoing SURPASS-COVT study (ClinicalTrials.gov number, NCT04255433), which compares tirzepatide with dulaglutide in patients with T2DM and ASCVD

thus, glomerular pressure increases and leads to glomerular hyperfiltration until organ damage develops [84]
