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After removing 420 duplicates and excluding 23 articles prior to screening, 1,509 records remained for title and abstract review

Safety, efficacy, and cardiovascular benefits of combination therapy with SGLT-2 inhibitors and GLP-1 receptor agonists in patients with diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials

Published 2023 Feb 3

(15), a sub-analysis found that GLP-1RAs are safe in patients with HF and in fact reduces their risk of hospitalisation for HF

Key symptoms Persistent feeling of queasiness or the urge to vomit Increased salivation (watering mouth) Retching or dry heaving Actual vomiting of stomach contents Loss of appetite Potential dehydration if vomiting is severe How common are nausea and vomiting with GLP-1 treatments
