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Semaglutide has been studied in clinical trials lasting more than a year and is generally considered safe for long-term use under medical supervision

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The label expansion was supported by two Phase III trialsa 12-week induction study and a 52-week maintenance studyboth of which met the primary endpoint of clinical remission

Under the gesetzliche Krankenversicherung (GKV) public insurance system, GLP-1 medicines including Ozempic are covered when prescribed for type 2 diabetes

The metformin research suggests plausibility for similar effects with semaglutide , but the mechanisms differ enough that direct extrapolation remains uncertain