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Prescription weight loss medications: GLP-1 medications like Mounjaro have extensive clinical evidence showing 15-25% weight loss

GLP-1 Antidiabetic Medications Glucagon-like Peptide-1 (GLP-1) agonists are injectable medications used to treat Type 2 diabetes and may also cause weight loss

128 Cyclosporine has been identified as a substrate for CYP3A4, P-glycoprotein (P-gp), and organic anion transporting polypeptides (OATPs), while also acting as a potent inhibitor of CYP3A4, multidrug resistance-associated protein 2 (MRP2), OATPs, P-gp, and breast cancer resistance protein (BCRP)

Previous studies have demonstrated that the deficiency of monoaminergic neurotransmitters, such as 5-HT, norepinephrine (NE), and dopamine (DA), aggravates depressive behaviors and can be used as a diagnostic index for depression (Massart et al., 2012