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-Cell-specific protein kinase A activation enhances the efficiency of glucose control by increasing acute-phase insulin secretion

Liraglutide is also marketed as a diabetes drug under the name Victoza

One was a mature glucagon and the other was called the proglucagon fragment

Considering the short half-life of small molecule oral GLP-1 receptor agonists, perhaps approaches to increase the duration of small molecules with a modified-release formulation may lead to improvements in long-term cardiovascular benefits

doi: 10.1530/EDM-21-0007 [DOI] [PMC free article] [PubMed] [Google Scholar] 193