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In our April issue of , Chris Aiken and David Liebers take a hard look at where these drugs really fit ( Highlights: , : GLP-1s can reverse antipsychotic weight gainsomething metformin rarely achieves once weight is established

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Clinically, it is used as an opioid analgesic for the relief of moderate to severe pain or acute and chronic pain

As a result, they are effective treatment options for people with T2D, achieving glycated haemoglobin reductions, weight loss and potential cardiovascular benefit, as monotherapy or as add-on to other glucose-lowering therapies