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PD-L1 chimeric costimulatory receptor improves the efficacy of CAR-T cells for PD-L1-positive solid tumors and reduces toxicity in vivo

Participants in trials have seen improvements in cholesterol, inflammation markers, and overall metabolic health

James David Lawrence III MD Georgia States Licenses: ARIZONA MEDICAL BOARD : 68332 COLORADO MEDICAL BOARD : CDR.0002247 CONNECTICUT DEPARTMENT OF PUBLIC HEALTH : 072839 DC BOARD OF MEDICINE : MD600001885 DELAWARE BOARD OF MEDICAL LICENSURE AND DISCIPLINE : C1-0025576 HAWAII MEDICAL BOARD : Md-24989-0 IDAHO BOARD OF MEDICINE : MC-1745 ILLINOIS DIVISION OF PROFESSIONAL REGULATION : 036.162756 INDIANA MEDICAL LICENSING BOARD : 01094116A IOWA BOARD OF MEDICINE : MD-53703 KENTUCKY BOARD OF MEDICAL LICENSURE : C1132 LOUISIANA MEDICAL BOARD : 334012 MAINE BOARD OF LICENSURE IN MEDICINE : MD26568 MARYLAND BOARD OF PHYSICIANS : D0095793 MICHIGAN BOARD OF MEDICINE : EMC0002605 MINNESOTA BOARD OF MEDICAL PRACTICE : 72801 MISSISSIPPI STATE BOARD OF MEDICAL LICENSURE : 30850 MONTANA BOARD OF MEDICAL EXAMINERS : MED-PHYS-COM-LIC-117085 NEBRASKA BOARD OF MEDICINE AND SURGERY : 35294 NEW HAMPSHIRE BOARD OF MEDICINE : 23371 NEW JERSEY STATE BOARD OF MEDICAL EXAMINERS : 25IA12312600 NORTH DAKOTA BOARD OF MEDICINE : 19108 OHIO MEDICAL BOARD : 35C.000204 OKLAHOMA STATE BOARD OF MEDICAL LICENSURE & SUPERVISION : 40577 PENNSYLVANIA STATE BOARD OF MEDICINE : MD487353C TENNESSEE BOARD OF MEDICAL EXAMINERS : 67189 VERMONT BOARD OF MEDICAL PRACTICE : 042.0016574 WASHINGTON MEDICAL COMMISSION : IMLC.MD.61373018 WEST VIRGINIA BOARD OF MEDICINE : 31907 WYOMING BOARD OF MEDICINE : 15150C

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This class of medication has been available for a while, but these drugs really became popular in the past couple years because of their effects on weight management, co-author Serena Jingchuan Guo, MD, PhD, associate professor and AI director at Purdue University College of Pharmacy, told Healio