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These cytokines are sufficient and necessary for inducing both astrocyte transformation into neurotoxic A1 and blood-retina barrier destruction, resulting in the subsequent retinal ganglia cell death and various ophthalmopathy (Figure 4
JCI Insight 5(6):e133429 Drucker DJ (2018) Mechanisms of action and therapeutic application of glucagon-like peptide-1

However, the future impact of these policies combined with mounting competitive pressures may already be altering pricing dynamics

I 2 = 27%) compared with metformin, but not for HbA1c (MD: -0.05, 95% CI: -0.19, 0.09

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