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However, experts cautioned that the findings are still preliminary

The benefits of GLP-1 RAs are derived from their pleiotropic effects, which include glucose-dependent insulin secretion, suppressed glucagon secretion, and reduced appetite

Within this framework, absorption can be considered a metabolic control module: even when dietary composition appears adequate, altered gastrointestinal kinetics may reduce effective delivery of critical substrates, shifting metabolic constraint from nutrient intake to handling efficiency

In a contemporary cohort of 16,492 patients with T2D and at high/very high CV risk participating in the SAVOR-TIMI 53 trial [6], CVD remained the leading cause of death and approximately one-third of all deaths were classified as sudden

GLP-1RAs stimulate insulin secretion in a glucose-dependent manner, therefore, reduce the risk of hypoglycemia