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Strategies to correct the incretin defects in patients with type 2 diabetes include replacement of GLP-1 with a long-acting analog that resists degradation and development of drugs that inhibit the enzyme DPP-4, which breaks down GLP-1

This is reassuring, but the data in humans is still limited, and larger studies are needed to fully understand how these medications affect fertility and pregnancy (12,13)

The company will continue to cover these drugs for diabetes treatment and may offer large employers the option to keep weight-loss coverage

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