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Further detailed investigations of GLP-1R V229A behaviours in beta cells revealed an overall reduction in cholesterol binding under vehicle conditions, which correlated with reduced lateral diffusion, average displacement, and speed of movement across the plasma membrane of the V229A receptor under these conditions

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Data from other groups and our recent study have shown that endothelium and cardiac and vascular myocytes express a functional GLP-1R, and participate in the protective cardiovascular effects of GLP-1 analogues 11,36,37,38

Retrieved 6 March 2019

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