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This distinguishes these agents from sodium-glucose cotransporter-2 (SGLT2) inhibitors, another diabetes medication class that does carry a well-documented increased risk of genital mycotic infections due to their mechanism of causing glucosuria

The device is designed to be straightforward and is well-suited to patients who are new to self-injection or who prefer not to handle syringes and vials

Intracerebroventricular application of GLP-1R agonist binds to GLP-1R on both neurons and astrocytes in the NTS

It's a story about economics, about a market that's been stretched to its breaking point

FDA prescribing information for some GLP-1 receptor agonists (particularly those approved for weight management) includes recommendations to monitor heart rate at regular intervals and consider discontinuation for sustained increases in resting heart rate