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A study analyzing endometrial HOXA10 and HOXA11 levels during the WOI in infertile women with intramural UFs found significantly decreased levels of HOXA10 and HOXA11 and a slight decrease in E-cadherin compared to healthy fertile women (Makker et al., 2017)

Because GLP-1 receptor agonists have demonstrated anti-inflammatory, weight-reducing, and cardiometabolic benefits in other populations, researchers hypothesized that these agents could provide advantages for patients with HS as well

Some included studies also examined artificially sweetened beverages, which generally showed minimal or no effect on sperm health, but further research is needed to clarify these findings