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Categorical variables were compared across groups using chi-squared tests, and continuous variables were compared using analysis of variance (ANOVA)

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Specifically, among patients who had at least three GLP-1RA prescriptions, we assessed the average percent change in weight in the year leading up to the date of their last prescription (defined as month 0) and in the six months following their last prescription (post-cessation). Separate analyses were performed for tirzepatide (Figure 1A) and semaglutide (Figure 1B), enabling a consistent comparison across agents