contraindications for glp-1 agonists include Safety and Tolerability of Glucagon-Like Peptide-1 Receptor Agonists: A State-of-the-Art Narrative Review | Drugs Non-insulin injectable antidiabetic drugs -
Description
Several indirect mechanisms may explain why some patients report muscle pain or weakness while taking GLP-1 medications, even in the absence of direct myotoxicity

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This study suggests that GLP-1 can enhance the function of brown fat, increase heat production in BAT, and reduce body weight in mice by modulating the activity of the sympathetic system through binding with GLP-1R in the center

P = 0.006) or metformin (OR = 1.37
