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This mechanism supports cellular resilience by upregulating endogenous antioxidants, including heme oxygenase-1 (HO-1), thus reducing oxidative stress, preventing mitochondrial dysfunction, and limiting apoptosis [11, 20, 23, 41, 42]

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doi: 10.1111/j.1365-2036.2008.03870.x [DOI] [PubMed] [Google Scholar] 25
