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doi:10.1038/s41573-021-00337-8 24

Their proven effectiveness in helping people lose weight means the medications represent a new chapter in how health services can treat obesity and the killer diseases it causes, the WHO added

Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately controlled with metformin (TOSCA.IT): a randomised, multicentre trial

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For more formal quantification, validated screeners include the Physical Activity as a Vital Sign questionnaire [127] and the International Physical Activity Questionnaire [128]
