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Longitudinal Targeted Minimum Loss-based Estimation, a method that adjusts for both baseline and time-varying confounding, was used to estimate absolute risks of cardiovascular outcomes under sustained use of GLP1-RA and DPP 4i (active comparator), adjusting for baseline and time-varying confounding

In an attempt to develop a strategy to prolong the physiological t1/2 and enhance the potency of GLP-1, a fusion protein consisting of active human GLP-1 and mouse IgG1 heavy chain constant regions (GLP-1/Fc) was generated
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