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Glucagon-like peptide-1 receptor agonists (GLP-1RAs), such as semaglutide and tirzepatide, have emerged as transformative agents for type 2 diabetes and obesity through their potent effects on weight reduction, insulin sensitivity, and cardiovascular outcomes

After four years of following patients taking Wegovy, the trial revealed how quickly it worked, if patients kept the weight off -- and something else surprising.

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Semaglutide can accelerate fat loss, but without proper nutrition and supplementation, muscle tissue may decline alongside body weight