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The HRMS software workflow generates b- and y-ion series from MS/MS fragmentation, enabling unambiguous localisation of modifications for instance, confirming whether an oxidation event sits on Met or on the Trp residue of a specific sequence position
This bidirectional signaling pathway connecting the gastrointestinal tract and the central nervous system involves mechanisms associated with the intestinal peptides, in particular human incretin hormones such as anorexigenic GLP-1
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