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Adults who have a BMI index of 30 kg/m^2 or higher (obesity) or 27 kg/m^2 or greater (overweight) with at least one weight-related health problem (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia) may benefit from GLP-1 injections combined with physical activity and a reduced calorie diet [11]

Approved in 2017 to treat tardive dyskinesia, Ingrezza is a selective vesicular monoamine transporter 2 inhibitor

These were randomised controlled trials, not observational data

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In addition to name-brand meds, compounded versions are also available