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After the initial 4 months, a subset of participants (270) continued the treatment for an additional 42 months in a single-blind extension phase, focused on weight maintenance

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It performs three primary roles: it prompts the pancreas to release insulin, signals the brain to feel full, and slows down the speed at which food leaves the stomach

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Clinical data from STEP trials (which evaluated semaglutide efficacy in weight management) relied on medications stored under strict temperature controls

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A comprehensive meta-analysis published in 2020 examined 12 randomized controlled trials involving berberine for weight management

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Energy and Cognitive Support B12 supports brain function and helps counter fatigue during weight loss

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