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Key strengths include well-designed randomized controlled trials demonstrating significant weight loss and metabolic benefits

For research purposes, mazdutide belongs to the incretin mimetic family of peptides

By engaging the glucagon receptor in addition to the two incretin receptors, retatrutide is hypothesized to add a direct energy-expenditure component to the appetite-suppressing and glucose-regulating effects already established for GLP-1 and GIP agonism

In addition to changes at the formulary, benefit design and utilization management levels, successfully managing GLP-1 agonists requires extra support for members

Its also important to work with your healthcare provider to address any potential contributing factors