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[DOI] [PMC free article] [PubMed] [Google Scholar] 2.GLP-1 receptor agonists: an updated review of head-to-head clinical studies

The American College of Gastroenterology notes that physical activity can be a helpful complementary approach to managing constipation, though evidence for its effectiveness as a standalone treatment is modest

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Patients should consult their healthcare provider for personalized dose instructions and adjustments

What Each Compound Does Retatrutide (LY3437943) is a triple agonist: GLP-1 (cuts appetite, slows the stomach), GIP (improves insulin signaling), and glucagon (raises energy use and fat burning)