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Insulin is crucial in activating various growth factors that further stimulate brain receptors, thereby regulating mitochondrial functionality, cellular energy utilization, cell survival, and synaptic processes [33,35]

Those are legitimate research directions, but they remain secondary endpoints and specific-population findings not a general cardiovascular-outcomes claim

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MarketScan contains claims information provided by a sample of large employer plans, made representative of the ESI market by using weights to match counts in the Current Population Survey for enrollees at firms of 1,000 or more workers, adjusting by sex, age, and state

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