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Medications that facilitate reductions in alcohol use while achieving broad clinical uptake would fill a critical unmet need. The phase 2, double-blind, parallel-arm trial recruited 48 non-treatment-seeking patients with AUD at an academic medical center in the U.S

Both Tirzepatide and Retatrutide are designed for once-weekly administration, indicating their extended half-lives in research models

doi: 10.1007/s00213-024-06637-2 [DOI] [PMC free article] [PubMed] [Google Scholar] 33.Marty VN, Farokhnia M, Munier JJ, Mulpuri Y, Leggio L, Spigelman I

Future trials are essential to confirm these renal benefits and their applicability across diverse patient populations