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N Engl J Med 2019;381:841e51

It's not just a passive tank or storage tank for glucose

This has nothing to do with tirzepatide and everything to do with the temporary effect contrast dye can have on kidney function, which could impair metformin clearance

Bottom line Tirzepatide (the active ingredient in the GIP/GLP-1 medications Mounjaro and Zepbound) has become one of the most talked-about medications for weight loss, diabetes, and sleep apneathanks to its powerful effects on appetite, blood sugar, and body weight

They may encourage you to drink plenty of water throughout the day, enjoy nutritious foods, and make other changes that will serve you well long into the future