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When to Contact Your Provider Reach out to your healthcare provider immediately if you experience severe or ongoing vomiting, diarrhea, fainting, or seizures

The evolving landscape of obesity pharmacotherapy Nature Reviews Drug Discovery, 2026 1 Obesity pharmacotherapy has moved from weight loss drugs to cardiometabolic disease-modifying therapy Obesity is now framed as a chronic, relapsing, neuroendocrine-metabolic disease, not simply a lifestyle failure

This also increases local blood flow to the muscles, thereby improving substrate utilization

STEP 2 patients also had type 2 diabetes

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