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While beneficial for patients with obesity and metabolic syndrome, unintended weight loss can be detrimental in Crohn's disease patients who already struggle with malnutrition, malabsorption, or disease-related cachexia

The addition of an SGLT2i to existing GLP-1RA use was also associated with a reduced risk of CV mortality and heart failure compared with GLP-1RAs alone[72]

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[5] Further information is available on the NHS medicines pages for Wegovy and Mounjaro

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