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In the SURMOUNT-1 trial, tirzepatide produced dose-dependent weight reductions, with average losses approaching or exceeding ~20% at higher doses in adults with obesity who did not have diabetes, numbers that markedly exceed historical pharmacotherapy benchmarks

GLP-1 receptor agonists still suppress alpha-cell function even if beta-cell function is already impaired and can bring glucagon levels down to normal levels seen in healthy individuals 6

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Studies reveal that many people regain a large portion of the weight they initially lost sometimes as much as two-thirds within a year of stopping medications like semaglutide

Shima Hadidchi, MD Family Practice, we are committed to staying at the forefront of medical advancements