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Compliance with Ethics Guidelines This article is based on previously conducted clinical trials and does not contain any studies with human participants or animals performed by any of the authors

Past, present and future perspectives in NAFLD and MAFLD

Clinical data Decreased appetite was reported in 18-19% of participants at the 9mg and 12mg doses in the Phase 3 TRIUMPH-4 trial, compared to 9.4% on placebo

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In SURMOUNT2, eligible study participants were randomized to receive once weekly tirzepatide 10, 15 mg or a matching placebo for 72 weeks