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Clifford says

Maintaining a stable, cold environment ensures that the molecular binding affinity remains completely uncompromised over the duration of a lengthy study
small molecules are the new frontier

Large, persistent foam on the surface of the solution is a different matter
It encompasses trials SURPASS from 1 to 6 ( Figure 3A ), SURPASS-J (mono and combo) and SURPASS-AP, performed respectively on Japanese and Asian-Pacific population ( Figure 3B ), and SURPASS CVOT
