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GLP-1 receptor agonist (GLP-1RA)

Meurot C, Jacques C, Martin C, et al

Abdominal distension, early satiety, and gastroesophageal reflux symptoms may also develop as consequences of prolonged gastric retention

Since the discovery and functional verification of GLP-1 in the 1980s ( However, the therapeutic utility of native GLP-1 was limited by its rapid enzymatic degradation and short plasma half-life, which prompted the development of longer-acting receptor agonists

Victoza (liraglitude) A once-daily injectable that has been licensed to treat type 2 diabetes may also be used off-label to help individuals decrease their weight